fold gene symbol description id change p value Search Results


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Broad Institute Inc gsea platform
Myh9 deficiency promotes colitis-related adenoma formation (A) Oncomine analysis shows that the Myh9 mRNA expression is reduced in multiple types of gastrointestinal tumors in the TCGA database. C, no value (22); 1, cecum adenocarcinoma (22); 2, colon adenocarcinoma (101); 3, colon mucinous adenocarcinoma (22); 4, rectal adenocarcinoma (60); 5, rectal mucinous adenocarcinoma (6); 6, rectosigmoid adenocarcinoma (3); 7, rectosigmoid mucinous adenocarcinoma (1). (B) <t>GSEA</t> analysis of the transcriptome showing an enrichment of colorectal adenomas in Myh9 -KO mice. (C) Relative body weight of control and Myh9- KO mice upon AOM/DSS treatment. Body weight was normalized to the first day of TAM injection. The data represent mean ± SD derived from six mice for control group and five mice for Myh9 KO group. (D) Representative colon of control and Myh9 -KO mice after AOM/DSS treatment. Alcian blue staining was to improve observable adenomas in the colon. Right: quantification of adenoma numbers. The data represent mean ± SD derived from five mice per group. ∗ p < 0.05, Student's t test. (E) H&E staining shows the adenoma in colon from control and Myh9 -KO mice after AOM/DSS treatment. Scale bars, 200 μm.
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Genomatix gmbh network and pathway analysis (geps) system
Myh9 deficiency promotes colitis-related adenoma formation (A) Oncomine analysis shows that the Myh9 mRNA expression is reduced in multiple types of gastrointestinal tumors in the TCGA database. C, no value (22); 1, cecum adenocarcinoma (22); 2, colon adenocarcinoma (101); 3, colon mucinous adenocarcinoma (22); 4, rectal adenocarcinoma (60); 5, rectal mucinous adenocarcinoma (6); 6, rectosigmoid adenocarcinoma (3); 7, rectosigmoid mucinous adenocarcinoma (1). (B) <t>GSEA</t> analysis of the transcriptome showing an enrichment of colorectal adenomas in Myh9 -KO mice. (C) Relative body weight of control and Myh9- KO mice upon AOM/DSS treatment. Body weight was normalized to the first day of TAM injection. The data represent mean ± SD derived from six mice for control group and five mice for Myh9 KO group. (D) Representative colon of control and Myh9 -KO mice after AOM/DSS treatment. Alcian blue staining was to improve observable adenomas in the colon. Right: quantification of adenoma numbers. The data represent mean ± SD derived from five mice per group. ∗ p < 0.05, Student's t test. (E) H&E staining shows the adenoma in colon from control and Myh9 -KO mice after AOM/DSS treatment. Scale bars, 200 μm.
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Myh9 deficiency promotes colitis-related adenoma formation (A) Oncomine analysis shows that the Myh9 mRNA expression is reduced in multiple types of gastrointestinal tumors in the TCGA database. C, no value (22); 1, cecum adenocarcinoma (22); 2, colon adenocarcinoma (101); 3, colon mucinous adenocarcinoma (22); 4, rectal adenocarcinoma (60); 5, rectal mucinous adenocarcinoma (6); 6, rectosigmoid adenocarcinoma (3); 7, rectosigmoid mucinous adenocarcinoma (1). (B) <t>GSEA</t> analysis of the transcriptome showing an enrichment of colorectal adenomas in Myh9 -KO mice. (C) Relative body weight of control and Myh9- KO mice upon AOM/DSS treatment. Body weight was normalized to the first day of TAM injection. The data represent mean ± SD derived from six mice for control group and five mice for Myh9 KO group. (D) Representative colon of control and Myh9 -KO mice after AOM/DSS treatment. Alcian blue staining was to improve observable adenomas in the colon. Right: quantification of adenoma numbers. The data represent mean ± SD derived from five mice per group. ∗ p < 0.05, Student's t test. (E) H&E staining shows the adenoma in colon from control and Myh9 -KO mice after AOM/DSS treatment. Scale bars, 200 μm.
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Myh9 deficiency promotes colitis-related adenoma formation (A) Oncomine analysis shows that the Myh9 mRNA expression is reduced in multiple types of gastrointestinal tumors in the TCGA database. C, no value (22); 1, cecum adenocarcinoma (22); 2, colon adenocarcinoma (101); 3, colon mucinous adenocarcinoma (22); 4, rectal adenocarcinoma (60); 5, rectal mucinous adenocarcinoma (6); 6, rectosigmoid adenocarcinoma (3); 7, rectosigmoid mucinous adenocarcinoma (1). (B) <t>GSEA</t> analysis of the transcriptome showing an enrichment of colorectal adenomas in Myh9 -KO mice. (C) Relative body weight of control and Myh9- KO mice upon AOM/DSS treatment. Body weight was normalized to the first day of TAM injection. The data represent mean ± SD derived from six mice for control group and five mice for Myh9 KO group. (D) Representative colon of control and Myh9 -KO mice after AOM/DSS treatment. Alcian blue staining was to improve observable adenomas in the colon. Right: quantification of adenoma numbers. The data represent mean ± SD derived from five mice per group. ∗ p < 0.05, Student's t test. (E) H&E staining shows the adenoma in colon from control and Myh9 -KO mice after AOM/DSS treatment. Scale bars, 200 μm.
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RStudio ggplot2 package
Myh9 deficiency promotes colitis-related adenoma formation (A) Oncomine analysis shows that the Myh9 mRNA expression is reduced in multiple types of gastrointestinal tumors in the TCGA database. C, no value (22); 1, cecum adenocarcinoma (22); 2, colon adenocarcinoma (101); 3, colon mucinous adenocarcinoma (22); 4, rectal adenocarcinoma (60); 5, rectal mucinous adenocarcinoma (6); 6, rectosigmoid adenocarcinoma (3); 7, rectosigmoid mucinous adenocarcinoma (1). (B) <t>GSEA</t> analysis of the transcriptome showing an enrichment of colorectal adenomas in Myh9 -KO mice. (C) Relative body weight of control and Myh9- KO mice upon AOM/DSS treatment. Body weight was normalized to the first day of TAM injection. The data represent mean ± SD derived from six mice for control group and five mice for Myh9 KO group. (D) Representative colon of control and Myh9 -KO mice after AOM/DSS treatment. Alcian blue staining was to improve observable adenomas in the colon. Right: quantification of adenoma numbers. The data represent mean ± SD derived from five mice per group. ∗ p < 0.05, Student's t test. (E) H&E staining shows the adenoma in colon from control and Myh9 -KO mice after AOM/DSS treatment. Scale bars, 200 μm.
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CEM Corporation genes with > log2 fold change (cem/wt_btz and cem/btz7)
Myh9 deficiency promotes colitis-related adenoma formation (A) Oncomine analysis shows that the Myh9 mRNA expression is reduced in multiple types of gastrointestinal tumors in the TCGA database. C, no value (22); 1, cecum adenocarcinoma (22); 2, colon adenocarcinoma (101); 3, colon mucinous adenocarcinoma (22); 4, rectal adenocarcinoma (60); 5, rectal mucinous adenocarcinoma (6); 6, rectosigmoid adenocarcinoma (3); 7, rectosigmoid mucinous adenocarcinoma (1). (B) <t>GSEA</t> analysis of the transcriptome showing an enrichment of colorectal adenomas in Myh9 -KO mice. (C) Relative body weight of control and Myh9- KO mice upon AOM/DSS treatment. Body weight was normalized to the first day of TAM injection. The data represent mean ± SD derived from six mice for control group and five mice for Myh9 KO group. (D) Representative colon of control and Myh9 -KO mice after AOM/DSS treatment. Alcian blue staining was to improve observable adenomas in the colon. Right: quantification of adenoma numbers. The data represent mean ± SD derived from five mice per group. ∗ p < 0.05, Student's t test. (E) H&E staining shows the adenoma in colon from control and Myh9 -KO mice after AOM/DSS treatment. Scale bars, 200 μm.
Genes With > Log2 Fold Change (Cem/Wt Btz And Cem/Btz7), supplied by CEM Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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GraphPad Software Inc histograms of upregulated genes
Myh9 deficiency promotes colitis-related adenoma formation (A) Oncomine analysis shows that the Myh9 mRNA expression is reduced in multiple types of gastrointestinal tumors in the TCGA database. C, no value (22); 1, cecum adenocarcinoma (22); 2, colon adenocarcinoma (101); 3, colon mucinous adenocarcinoma (22); 4, rectal adenocarcinoma (60); 5, rectal mucinous adenocarcinoma (6); 6, rectosigmoid adenocarcinoma (3); 7, rectosigmoid mucinous adenocarcinoma (1). (B) <t>GSEA</t> analysis of the transcriptome showing an enrichment of colorectal adenomas in Myh9 -KO mice. (C) Relative body weight of control and Myh9- KO mice upon AOM/DSS treatment. Body weight was normalized to the first day of TAM injection. The data represent mean ± SD derived from six mice for control group and five mice for Myh9 KO group. (D) Representative colon of control and Myh9 -KO mice after AOM/DSS treatment. Alcian blue staining was to improve observable adenomas in the colon. Right: quantification of adenoma numbers. The data represent mean ± SD derived from five mice per group. ∗ p < 0.05, Student's t test. (E) H&E staining shows the adenoma in colon from control and Myh9 -KO mice after AOM/DSS treatment. Scale bars, 200 μm.
Histograms Of Upregulated Genes, supplied by GraphPad Software Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Pasteuria Bioscience LLC pasteuria s1
Myh9 deficiency promotes colitis-related adenoma formation (A) Oncomine analysis shows that the Myh9 mRNA expression is reduced in multiple types of gastrointestinal tumors in the TCGA database. C, no value (22); 1, cecum adenocarcinoma (22); 2, colon adenocarcinoma (101); 3, colon mucinous adenocarcinoma (22); 4, rectal adenocarcinoma (60); 5, rectal mucinous adenocarcinoma (6); 6, rectosigmoid adenocarcinoma (3); 7, rectosigmoid mucinous adenocarcinoma (1). (B) <t>GSEA</t> analysis of the transcriptome showing an enrichment of colorectal adenomas in Myh9 -KO mice. (C) Relative body weight of control and Myh9- KO mice upon AOM/DSS treatment. Body weight was normalized to the first day of TAM injection. The data represent mean ± SD derived from six mice for control group and five mice for Myh9 KO group. (D) Representative colon of control and Myh9 -KO mice after AOM/DSS treatment. Alcian blue staining was to improve observable adenomas in the colon. Right: quantification of adenoma numbers. The data represent mean ± SD derived from five mice per group. ∗ p < 0.05, Student's t test. (E) H&E staining shows the adenoma in colon from control and Myh9 -KO mice after AOM/DSS treatment. Scale bars, 200 μm.
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ATCC control cells
Myh9 deficiency promotes colitis-related adenoma formation (A) Oncomine analysis shows that the Myh9 mRNA expression is reduced in multiple types of gastrointestinal tumors in the TCGA database. C, no value (22); 1, cecum adenocarcinoma (22); 2, colon adenocarcinoma (101); 3, colon mucinous adenocarcinoma (22); 4, rectal adenocarcinoma (60); 5, rectal mucinous adenocarcinoma (6); 6, rectosigmoid adenocarcinoma (3); 7, rectosigmoid mucinous adenocarcinoma (1). (B) <t>GSEA</t> analysis of the transcriptome showing an enrichment of colorectal adenomas in Myh9 -KO mice. (C) Relative body weight of control and Myh9- KO mice upon AOM/DSS treatment. Body weight was normalized to the first day of TAM injection. The data represent mean ± SD derived from six mice for control group and five mice for Myh9 KO group. (D) Representative colon of control and Myh9 -KO mice after AOM/DSS treatment. Alcian blue staining was to improve observable adenomas in the colon. Right: quantification of adenoma numbers. The data represent mean ± SD derived from five mice per group. ∗ p < 0.05, Student's t test. (E) H&E staining shows the adenoma in colon from control and Myh9 -KO mice after AOM/DSS treatment. Scale bars, 200 μm.
Control Cells, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Exosome Diagnostics exosome marker proteins
Myh9 deficiency promotes colitis-related adenoma formation (A) Oncomine analysis shows that the Myh9 mRNA expression is reduced in multiple types of gastrointestinal tumors in the TCGA database. C, no value (22); 1, cecum adenocarcinoma (22); 2, colon adenocarcinoma (101); 3, colon mucinous adenocarcinoma (22); 4, rectal adenocarcinoma (60); 5, rectal mucinous adenocarcinoma (6); 6, rectosigmoid adenocarcinoma (3); 7, rectosigmoid mucinous adenocarcinoma (1). (B) <t>GSEA</t> analysis of the transcriptome showing an enrichment of colorectal adenomas in Myh9 -KO mice. (C) Relative body weight of control and Myh9- KO mice upon AOM/DSS treatment. Body weight was normalized to the first day of TAM injection. The data represent mean ± SD derived from six mice for control group and five mice for Myh9 KO group. (D) Representative colon of control and Myh9 -KO mice after AOM/DSS treatment. Alcian blue staining was to improve observable adenomas in the colon. Right: quantification of adenoma numbers. The data represent mean ± SD derived from five mice per group. ∗ p < 0.05, Student's t test. (E) H&E staining shows the adenoma in colon from control and Myh9 -KO mice after AOM/DSS treatment. Scale bars, 200 μm.
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Myh9 deficiency promotes colitis-related adenoma formation (A) Oncomine analysis shows that the Myh9 mRNA expression is reduced in multiple types of gastrointestinal tumors in the TCGA database. C, no value (22); 1, cecum adenocarcinoma (22); 2, colon adenocarcinoma (101); 3, colon mucinous adenocarcinoma (22); 4, rectal adenocarcinoma (60); 5, rectal mucinous adenocarcinoma (6); 6, rectosigmoid adenocarcinoma (3); 7, rectosigmoid mucinous adenocarcinoma (1). (B) <t>GSEA</t> analysis of the transcriptome showing an enrichment of colorectal adenomas in Myh9 -KO mice. (C) Relative body weight of control and Myh9- KO mice upon AOM/DSS treatment. Body weight was normalized to the first day of TAM injection. The data represent mean ± SD derived from six mice for control group and five mice for Myh9 KO group. (D) Representative colon of control and Myh9 -KO mice after AOM/DSS treatment. Alcian blue staining was to improve observable adenomas in the colon. Right: quantification of adenoma numbers. The data represent mean ± SD derived from five mice per group. ∗ p < 0.05, Student's t test. (E) H&E staining shows the adenoma in colon from control and Myh9 -KO mice after AOM/DSS treatment. Scale bars, 200 μm.
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Myh9 deficiency promotes colitis-related adenoma formation (A) Oncomine analysis shows that the Myh9 mRNA expression is reduced in multiple types of gastrointestinal tumors in the TCGA database. C, no value (22); 1, cecum adenocarcinoma (22); 2, colon adenocarcinoma (101); 3, colon mucinous adenocarcinoma (22); 4, rectal adenocarcinoma (60); 5, rectal mucinous adenocarcinoma (6); 6, rectosigmoid adenocarcinoma (3); 7, rectosigmoid mucinous adenocarcinoma (1). (B) <t>GSEA</t> analysis of the transcriptome showing an enrichment of colorectal adenomas in Myh9 -KO mice. (C) Relative body weight of control and Myh9- KO mice upon AOM/DSS treatment. Body weight was normalized to the first day of TAM injection. The data represent mean ± SD derived from six mice for control group and five mice for Myh9 KO group. (D) Representative colon of control and Myh9 -KO mice after AOM/DSS treatment. Alcian blue staining was to improve observable adenomas in the colon. Right: quantification of adenoma numbers. The data represent mean ± SD derived from five mice per group. ∗ p < 0.05, Student's t test. (E) H&E staining shows the adenoma in colon from control and Myh9 -KO mice after AOM/DSS treatment. Scale bars, 200 μm.
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Image Search Results


Myh9 deficiency promotes colitis-related adenoma formation (A) Oncomine analysis shows that the Myh9 mRNA expression is reduced in multiple types of gastrointestinal tumors in the TCGA database. C, no value (22); 1, cecum adenocarcinoma (22); 2, colon adenocarcinoma (101); 3, colon mucinous adenocarcinoma (22); 4, rectal adenocarcinoma (60); 5, rectal mucinous adenocarcinoma (6); 6, rectosigmoid adenocarcinoma (3); 7, rectosigmoid mucinous adenocarcinoma (1). (B) GSEA analysis of the transcriptome showing an enrichment of colorectal adenomas in Myh9 -KO mice. (C) Relative body weight of control and Myh9- KO mice upon AOM/DSS treatment. Body weight was normalized to the first day of TAM injection. The data represent mean ± SD derived from six mice for control group and five mice for Myh9 KO group. (D) Representative colon of control and Myh9 -KO mice after AOM/DSS treatment. Alcian blue staining was to improve observable adenomas in the colon. Right: quantification of adenoma numbers. The data represent mean ± SD derived from five mice per group. ∗ p < 0.05, Student's t test. (E) H&E staining shows the adenoma in colon from control and Myh9 -KO mice after AOM/DSS treatment. Scale bars, 200 μm.

Journal: Stem Cell Reports

Article Title: Non-muscle myosin heavy chain 9 maintains intestinal homeostasis by preventing epithelium necroptosis and colitis adenoma formation

doi: 10.1016/j.stemcr.2021.03.027

Figure Lengend Snippet: Myh9 deficiency promotes colitis-related adenoma formation (A) Oncomine analysis shows that the Myh9 mRNA expression is reduced in multiple types of gastrointestinal tumors in the TCGA database. C, no value (22); 1, cecum adenocarcinoma (22); 2, colon adenocarcinoma (101); 3, colon mucinous adenocarcinoma (22); 4, rectal adenocarcinoma (60); 5, rectal mucinous adenocarcinoma (6); 6, rectosigmoid adenocarcinoma (3); 7, rectosigmoid mucinous adenocarcinoma (1). (B) GSEA analysis of the transcriptome showing an enrichment of colorectal adenomas in Myh9 -KO mice. (C) Relative body weight of control and Myh9- KO mice upon AOM/DSS treatment. Body weight was normalized to the first day of TAM injection. The data represent mean ± SD derived from six mice for control group and five mice for Myh9 KO group. (D) Representative colon of control and Myh9 -KO mice after AOM/DSS treatment. Alcian blue staining was to improve observable adenomas in the colon. Right: quantification of adenoma numbers. The data represent mean ± SD derived from five mice per group. ∗ p < 0.05, Student's t test. (E) H&E staining shows the adenoma in colon from control and Myh9 -KO mice after AOM/DSS treatment. Scale bars, 200 μm.

Article Snippet: Gene set enrichment analysis (GSEA) was performed with rank gene based on fold change on the GSEA platform of the Broad Institute ( http://www.broadinstitute.org/gsea/index.jsp ).

Techniques: Expressing, Control, Injection, Derivative Assay, Staining